One way Anova to check rate variation among different regions of a protein is significant or not
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3.8 years ago
mjoyraj ▴ 80

I have a protein sequence, which may be divided into different functional regions. I calculated the rate variation in different functional regions of the protein (e.g. 7/18 = 0.38, 282/597 = 0.47, 59/111 = 0.53, 16/30 = 0.53, 20/37 = 0.54, and 11/30 = 0.36). I want to check if the rate variation among different regions are significant. Can I use one way Anova to do it ? IS their any online tool or software available that will do the test. Suggestions will be highly appreciated.

Statistics • 645 views
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I would say classical ANOVA assumes equal variation between groups. https://en.wikipedia.org/wiki/Analysis_of_variance#Assumptions

It may happen that you're looking for a proportion test.

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Yes, actually test for checking difference between different proportions...

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https://stat.ethz.ch/R-manual/R-devel/library/stats/html/prop.test.html = this one looks suitable (see Examples on the bottom)

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