Question: Meta Analysis on RNA-seq data
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gravatar for Mozart
14 days ago by
Mozart200
Mozart200 wrote:

Hello there,

  1. I was reading this post and wondering what could be the best tool to perform meta-analysis for RNA-seq experiment. Is DESeq2 a good tool for that? I have heard about metaSeq and it seems to be good. Any experience with the latter, by any chance?

  2. another question is whether meta analysis could be done for comparing different cell types that have the same genotype. For example, same KO cells (compared to wt) isolated from different tissues, each gathered from ≠ labs?

thanks

rna-seq meta analysis • 97 views
ADD COMMENTlink written 14 days ago by Mozart200

There are various approaches to do that; however, I would suggest you go for Ranks based methods, such as robust rank aggregation. https://www.pnas.org/content/107/33/14621 This article may answer your other questions as well. It all depends on the biological experiments.

ADD REPLYlink written 12 days ago by Thind Amarinder30
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