How many samples are too few for Hardy Weinberg equilibrium test?
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3.7 years ago
curious ▴ 750

Trying to do QC on genotype data and want to run HWE test w/ plink.

I have 60 samples, which seems may be on the low side, but I can't find too much on how small of sample size is too small.

These guys seem to suggest 20 is too low: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400604

Does anyone have any experience with this?

gwas • 527 views
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