Question: Viral Genome Alignment in MAFFT
gravatar for mauricio.morales
4 weeks ago by
mauricio.morales0 wrote:

Hi! I want to do an alignment for 743 viral genomes (27-30 kb approximately) in MAFFT. All genomes are complete and downloaded from NCBI virus. I want to do the best alignment and have already performed 5 test alignments, but I need your suggestions and experience to get the best possible result.

What parameter do you suggest to use for a case like this? Thank you!

sequence alignment genome • 90 views
ADD COMMENTlink modified 4 weeks ago • written 4 weeks ago by mauricio.morales0

If these virii are closely related then you should be fine using default settings. Depending on alignment you get some manual editing may be warranted afterwards.

ADD REPLYlink modified 4 weeks ago • written 4 weeks ago by genomax91k
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