Normalizing multiple conditons all together
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3.9 years ago
Raheleh ▴ 260

Hello all,

I have expression profile of 5 different conditions with 2 different time point, all in one matrix.

I am using RMA to normalize them. Can I normalize them all together? or I have to normalize each condition with control group separately? If I normalize them all together don't I lose the biological differences? I searched but I couldn't find my answer.

I really appreciate any advice!

RMA microarray time-series • 648 views
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