Question: Publicly Available Bivalent Genes List [Mouse]
0
gravatar for Sukhdeep Singh
6.4 years ago by
Sukhdeep Singh9.6k
Netherlands
Sukhdeep Singh9.6k wrote:

Dear Community,

According to Dr.Bernstein paper, a bivalent gene is defined as a gene where both the K4me3 (active) and K27me3 (repressive) marks are observed. Thus, the gene is poised for transcription. One could overlap the K4me3 and K27me3 with a custom defined promoter list to generate a list of bivalent genes, but I would like to confirm my results.

My question is after 5 years, is there a publicly available or a tested/confirmed list of bivalent genes for the mouse ESC's.

Thanks

mouse chip-seq • 2.3k views
ADD COMMENTlink modified 5.6 years ago • written 6.4 years ago by Sukhdeep Singh9.6k

So you're looking for a list of bivalent genes that was built using a different criterion than that of Bernstein et al.?

ADD REPLYlink written 6.4 years ago by Ben2.0k

yeah, may be different methodology, like using ChIP-Seq, which might give a little different and better result.

ADD REPLYlink modified 6.4 years ago • written 6.4 years ago by Sukhdeep Singh9.6k
1
gravatar for Sukhdeep Singh
5.6 years ago by
Sukhdeep Singh9.6k
Netherlands
Sukhdeep Singh9.6k wrote:

BGDB: a database of bivalent genes accessible here for Human and Mouse http://dailab.sysu.edu.cn/bgdb/

ADD COMMENTlink written 5.6 years ago by Sukhdeep Singh9.6k
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