I have a membrane protein (~400 aa) in which >90% of the mutations result in the loss of activity. I was trying to use SVM to predict the effect of mutation. However it predicts loss of activity in all cases. Let me know if it is possible to use PSSM matrices along with SVM or other tools to better predict the effect of mutation.
Question: Predicting Effect Of Mutations In Terms Of Activity
8.2 years ago by
Pappu • 1.9k
Pappu • 1.9k wrote:
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