I was hoping to obtain some recommendations of available resources to find genes/pathways associated with a phenotype (not necessarily human).
I have some general phenotype information but I do not know which disease(s) it is associated with. I also have sequence data for the affected individuals. As a general starting point I was hoping to look for genes and pathways that might be associated with this phenotype. I was then going to link this knowledge to an analysis of any variations in the individuals. I am very receptive to alternative approaches though :)
I have seen OMIM and OMIA. I have also seen PhenomicDB and PhenoHM: human-mouse comparative phenome-genome server.
I am aware there is a myriad of GWAS resources linking markers to phenotypes but I was looking specifically for resources linking genes and pathways to phenotype. I have chosen (perhaps unwisely) not to focus too much on the GWAS studies because the marker identified by the study may not be the causal/functional SNP. I do have QTL data to narrow down my genomic regions of interest so hopefully that will compensate.
Please can you advise if I have missed any obvious useful resources or if there are any other strategies I could employ to get a starting point.
Thank you for your time