Question: Does The Reading Frame Of The Exon Always Start At The First Nucleotide
0
gravatar for davidvanijzendoorn
5.9 years ago by
davidvanijzendoorn0 wrote:

I have the sequence from an exon. Does the reading frame always start at the first nucleotide of the exon for when I want to translate it to an amino acid?

nucleotide exon • 1.9k views
ADD COMMENTlink modified 5.9 years ago by swbarnes26.9k • written 5.9 years ago by davidvanijzendoorn0
2
gravatar for swbarnes2
5.9 years ago by
swbarnes26.9k
United States
swbarnes26.9k wrote:

No, it doesn't. There's no way to know just by looking at an exon what frame is the right frame for translation.

ADD COMMENTlink written 5.9 years ago by swbarnes26.9k

If you know the length of your 5'UTR you can calculate the frame from the exon sequence, right?

ADD REPLYlink written 5.9 years ago by Phil S.660

If you know what position that exon sits in the whole transcript, then sure. But you can't know that from the sequence of an exon alone.

ADD REPLYlink written 5.9 years ago by swbarnes26.9k
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