Question: How To Calculate Recombination Rate From R^2 Data?
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gravatar for Adrian Pelin
6.7 years ago by
Adrian Pelin2.4k
Canada
Adrian Pelin2.4k wrote:

If all I have is NGS and a few isolates, is there any way to calculate recombination rate? Based on allele frequencies?

ngs recombination • 3.3k views
ADD COMMENTlink written 6.7 years ago by Adrian Pelin2.4k

Have you tried LDHAT?

ADD REPLYlink written 6.7 years ago by kumar.vinod81280

I know it is able to do it, I am however interested in the theory behind it. What does r^2 actually mean? I know it's association of different genotype frequencies, but what does it mean when it is very high or very low in terms of recombination?

ADD REPLYlink written 6.7 years ago by Adrian Pelin2.4k
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