I have 625 miRNAs, and I want to find their expressions (up/down regulated) using TCGA.
How can I make it?
You mean you want to check the differential expression of these miRNAs in Normal Vs. Tumor samples?
Yes Nitin Narwade
Usually, to test the difference in gene expression between two groups, I run Wilcox Test (a non-parametric test, which uses median to test the difference between two groups) using normal and tumor samples along with the fold change (using log2(median expression of a gene in each group)).
Maybe you can try something similar.
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