Best sequence alignment tool

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2.1 years ago

anonymous5982 ▴ 10

Hi-

I want to compare different sequence aligners for part of an assignment I am writing. I am seeing through the posts on here that the best choice of sequence aligner depends on the type of data you are working with.

I don't really have much knowledge of the field (as in I can't tell what type of data would be best to align with MUMmer or BWA for example). I am wondering whether there is a review paper to summarise what the best sequence aligner tool is given the type of dataset you have?

BWA alignment MUSCLE Sequence MUMmer • 444 views

ADD COMMENT • link updated 2.1 years ago by GenoMax 142k • written 2.1 years ago by anonymous5982 ▴ 10

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Pair-wise sequence aligners are a different class (e.g. bwa) of tools compared to multiple sequence alignment tools (e.g. MUSCLE). Which of the two are you interested in? What kind of data are you working with?

ADD REPLY • link 2.1 years ago by GenoMax 142k

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