Job:Senior Director, Bioinformatics - PDx (Post-Diagnostic Applications)
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13 months ago
Shawn Vyas ▴ 10

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

As the Executive/Senior Bioinformatics Leader, you will head up a team of bioinformatics scientists to analyze some of the largest, richest biological datasets in the world to find biological signals and patterns and guide our assays and develop new methods for future products. You will work with diverse teams including software, clinical, operations, research, product development, and external collaborators. Your work will result in exciting discoveries in cancer biology, impactful publications, and potential future products.

You will:

  • Lead, develop, and manage a team of bioinformatics scientists, engineers and researchers
  • Develop new bioinformatics approaches for analysis of large-scale genomics datasets and application development.
  • Collaborate with various internal teams including software, clinical, operations, research, and product development.
  • Act as bioinformatics functional lead for GRAIL’s external scientific collaborators.
  • End-to-end analysis that includes design, data gathering, processing, analysis, iteration with stakeholders, and presentation of results.
  • Promulgate approaches and build tools that preserve scientific rigor and quality.
  • Maintain an active external scientific presence.

Your background should include:

  • Ph.D. in Bioinformatics, Computational Biology, Statistics, Biological Sciences, Cancer Biology, Genetics, Genomics, Computer Science, Physics, or other industry-related field experience.
  • 10+ years proven experience in positions of growing responsibility.
  • Minimum 3 years, demonstrated ability to manage bioinformatics teams, provide technical leadership, perform translational research, leading cross functional projects.
  • Consistent track record of validated contributions proven by highly cited publications, impactful tools, products, or data sets used by the scientific community, presentations at international conferences, and awards.
  • Deep understanding of modern statistical and machine learning tools for analysis of genomics datasets.
  • Demonstrated expertise in at least one programming language (R, Python, Go, C++).
  • Proficiency in Linux environment, version control tools, and reproducible research practices.
  • Technical leadership and self-direction, willingness to both mentor others and learn techniques.
  • Excellent written and verbal communication skills.

To be successful in this role, you are:

  • Able communicate a clear vision for scientific and technical areas for long-term success of GRAIL.
  • Leads, owns and/or handles several scientific and technical areas.
  • Leads the organization to success, helping to craft high-level strategic direction with senior leadership and/or the executive team
  • Works with other leads to set policies and processes that span across multiple GRAIL organizations
  • Initiate and lead positive relationships across GRAIL and externally actively working with cross-functionally and at levels, including Executive and Senior Leadership
  • Able to lead multidimensional projects, collaborate with all collaborators including Senior and Executive Leadership, and act as a leader across GRAIL
  • Able to recognize interdependencies across functions and make necessary adjustments for timely meeting of GRAIL goals
  • Able to lead dissemination of key GRAIL achievement across GRAIL and externally
  • Influences and leads teams across GRAIL to achieve broader company goals as well as team goals within their organization.

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

senior-director • 586 views
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Looks like an awesome opportunity. Good luck filling :-)


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