encode gt of hg38 to machine learning
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8 days ago

Hi

I'm new in the field , I have a large vcf file that have many variants with many sample I extract gt for each sample / variants to get a matrix to do a machine learning algorithem

now, I need to encode this gt to do a machine learning I see a stranger numbers in gt like [-1 -1] , [1 5] , [ 1 6 ] , [ 0 -1] ,[ 1 -1],[ 2 -1] So , what is mean for hg38 ? and How can I encode to use a machine learning ?

machine_learning gt • 139 views
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I see a stranger numbers in gt like [-1 -1] , [1 5] , [ 1 6 ] , [ 0 -1] ,[ 1 -1],[ 2 -1]

where do you find this information in the VCF ? how do you extract the matrix ?

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I'm extracting gt using sckite allel package ( python ). when I compare what I actually extract and origenal vcf I found ( -1 = . ).

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