How to find the Allele Number (AN) of a variant not reported on gnomAD

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5 months ago

Lisa392 • 0

If there is a variant not reported on gnomAD, is there a way to determine the allele number to confirm how many people were sampled, and were not found to have that variant for a given chromosomal location?

gnomad variant • 462 views

ADD COMMENT • link updated 5 months ago by Jeremy Leipzig 22k • written 5 months ago by Lisa392 • 0

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You need to check with the gnomAD team - I'm not sure if they are the primary source for any of the data or they just reprocess sequencing data from other sources. If the latter is the case, you'll have to contact the primary sources.

ADD REPLY • link 5 months ago by Ram 43k

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at least for gnomad v3 the allele number is generally around 152,000 for variants they do see, so I would imagine that number would suffice for loci that have no reported variants enter image description here

ADD REPLY • link 5 months ago by Jeremy Leipzig 22k

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