No PhyloP score for first stretch of chromosome?
1
0
Entering edit mode
10.0 years ago
user ▴ 940

I'm looking at phyloP data from UCSC (http://hgdownload.cse.ucsc.edu/goldenPath/mm9/phyloP30way/vertebrate/). It looks like the first 3 million bases or so of some chromosomes don't have phyloP scores. Example:

$ zcat chr1.phyloP30way.wigFix.gz | head -n 5
fixedStep chrom=chr1 start=3000306 step=1
0.223
0.240
...

so the start position is 3000306. Why are there no scores for position 1 through 3000305?

alignment ucsc genome-browser phylop • 2.3k views
ADD COMMENT
3
Entering edit mode
10.0 years ago

From looking at the UCSC Genome Browser for mm9, say, along chr1, from bases 1 through 5M, it looks like protein-coding regions or gene transcript annotations (where conservation is measured) start a little past 3M bases. Here's a screenshot from the WashU Epigenome browser:

ADD COMMENT

Login before adding your answer.

Traffic: 2905 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6