Normalization is one of the main preprocessing step in bioinformatics data analysis. most of the time people just talk about the normalization methods that they have applied to their own data and they don't talk about that, whether they did nside sample and between samples normalization .
For me it's not clear that, when I should use inside sample normalization and when between samples normalization? Is there any rules of thumb for that?
Could you rephrase your question? It doesn't parse correctly into English as written. Also, the goal of the analysis can be important when thinking about normalization, so mention that as well.
Devon, I edited it.