How much of human genome transcribe? How much of transcriptome are non-coding RNAs?

Question

[jack]

Hi all,

I'm looking to understand, how many percent of human genome are transcribe? How much of transcriptome are protein coding an much are non-coding RNAs ?

[Manvendra Singh]

Exact number can not be given as this has cell type specificity. For example, there are much more non coding RNA and endogenous retroviral elements are expressed during development and in cancers which occupy much proportion of genome in comparison to that of normal differentiated cell types.

Answer 1

[Devon Ryan]

N.B. This is edited from the original, which was a post-closing comment. Due to that, some replies may not seem directly connected.

Have a look at this paper for some useful numbers.

In short, 5-10% of the human genome is transcribed and ~2% is protein coding.

[Istvan Albert]

I disagree a bit here. I think that we all need to have a good sense of the sizes and magnitudes because they help us choose the right approaches, provide sanity checks and other estimates. It may not be computing related but it affects computing greatly.

[Devon Ryan]

Fair enough.

[Istvan Albert]

I am going to move the comment to an answer because the link in there does actually provide all the answers.

[Devon Ryan]

OK, I've reformatted it more as an answer and left a note mentioning why there are seeming non sequitor comments.

[jack]

Istvan, you are completely right