Genome to Drug Variant

Question

[s.venkataramanan]

I am new to NGS data Analysis my supervisor told me to do NGS data Genome to Drug Variant

I have a NGS data which already identified some mutation related to Lung cancer

My question here is what I need to do

Is there any software or tutorial or method to followup the work

My supervisor ask me to do pharmacogenomics kind of work

Give me some tools/software/tutorials to proceed now

Thanks for helping me

[Devon Ryan]

So are you trying to predict effective drugs given a set of mutations or determine the effect of mutations on drug metabolism and/or efficacy? This is completely ambiguous from what you wrote, though I'm guessing the latter given your mention of pharmacogenomics.

Answer 1

[Kevin Blighe]

Some things have come about ~6 years later:

• Open Targets
• PharmGKB
• 3DSNP
• ORegAnno
• et cetera

Kevin