Question: Extracting gene subnetwork from pathways using gene expression data
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gravatar for Nicolas Rosewick
4.5 years ago by
Belgium, Brussels
Nicolas Rosewick8.3k wrote:

Hi,

I've a bunch of RNA-Seq data (treated vs untreated) and I want to map these expression data (analyzed with DESeq2) on known biological pathway such as KEGG or Reactome. and to extract subnetwork enriched in differentially expressed genes. Anyone knows good recent publications about this type of analysis ; or any advice to how to start the analysis: tools ? which pathway format (sif ? biopax ?)

Thanks you

ADD COMMENTlink modified 4.4 years ago by andrew470 • written 4.5 years ago by Nicolas Rosewick8.3k
0
gravatar for andrew
4.4 years ago by
andrew470
United States
andrew470 wrote:

One of our collaborators published on this in2013.  You can read the abstract and link to the paper from the science section of our website.  Here.

Analysis and correction of crosstalk effects in pathway analysis.

ADD COMMENTlink written 4.4 years ago by andrew470
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