Question: Extracting gene subnetwork from pathways using gene expression data
gravatar for Nicolas Rosewick
5.8 years ago by
Belgium, Brussels
Nicolas Rosewick9.3k wrote:


I've a bunch of RNA-Seq data (treated vs untreated) and I want to map these expression data (analyzed with DESeq2) on known biological pathway such as KEGG or Reactome. and to extract subnetwork enriched in differentially expressed genes. Anyone knows good recent publications about this type of analysis ; or any advice to how to start the analysis: tools ? which pathway format (sif ? biopax ?)

Thanks you

ADD COMMENTlink modified 5.7 years ago by andrew510 • written 5.8 years ago by Nicolas Rosewick9.3k
gravatar for andrew
5.7 years ago by
United States
andrew510 wrote:

One of our collaborators published on this in2013.  You can read the abstract and link to the paper from the science section of our website.  Here.

Analysis and correction of crosstalk effects in pathway analysis.

ADD COMMENTlink written 5.7 years ago by andrew510
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