Where to learn about getting a few thousand genomes sequenced?
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9.1 years ago
LauferVA 4.2k

Hello,

I am interested in learning more about how to determine what kind of resources are needed to sequence a few thousand genomes.

The actual sequencing and pricing I think I have, though I am hazy as to what type of file is currently delivered (do most people get you at least to a BAM file?) I am talking about:

  • buying storage and backup drives
  • computational power and processing
  • how many full time equivalents per 1000 genomes sequenced in terms of statistical analytics and programming expertise?

The goal here would be to ultimately learn this well enough to submit an intelligent proposal on it.

budget sequencing • 1.3k views
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Are we talking a few thousand human genomes or something else? Whole genome or exome only? Do you want SNPs, large structural rearrangements, to do de novo assembly, etc.? You post, as is, is to vague to give any real recommendations. You'll likely have to collaborate pretty broadly for this sort of project.

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~4000 whole human genomes. we are interested in structural variation as well.

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