Question: The reason two identical sequences have different accession numbers and different loci
0
gravatar for Michel Edwar
5.1 years ago by
Michel Edwar70
Sweden
Michel Edwar70 wrote:

 I am currently working on a certain gene.  I was looking for it in pigs among other species. In all the species investigated, I found a single copy. However, when I inspected the pigs genome,

I found two identical copies that, although have different genes accession numbers(XP_xx11, XP_xx2) , and  appear in two different loci  (loci 1, loci 2) , their nucleotide sequences  are identical. Would that suggest that the two genes are really identical ( two copies of the same gene ) or that could be a sequencing error?

copy number alignment • 1.7k views
ADD COMMENTlink modified 5.1 years ago by h.mon30k • written 5.1 years ago by Michel Edwar70
0
gravatar for h.mon
5.1 years ago by
h.mon30k
Brazil
h.mon30k wrote:

These genes may be assembly errors, but if they were given different GIs, it is more likely there is enough evidence they are real duplicates.

You don't describe anything about them and the context they are: are they located in short, fragmented contigs? Do they belong to olfactory, immunological, or other pathway where duplications are common? Did you investigate the flanking regions?
 

ADD COMMENTlink written 5.1 years ago by h.mon30k
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