Question: deflated lambda value but inflated qq plot
gravatar for muralinmars
5.0 years ago by
muralinmars80 wrote:

Dear all,

I frequently encounter this issue of deflated lambda values (eg. 0.8 - 0.99) but the qqplot looks inflated, when running the qq function in a gwas study.

Why does this happen, is this due to technical error or with the study sample...

Deflation shows that the study is underpowered so does the sample size has on effect on this issue...


url to the image



gwas qqplot R • 2.8k views
ADD COMMENTlink modified 5.0 years ago • written 5.0 years ago by muralinmars80

I have the reverse situation. Strange indeed!

ADD REPLYlink written 2.3 years ago by rmf940
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