In Drugbank, the Fluvastatin structure is at the beginning, while the salt form in the latter section of the webpage.
It seems the active form should be Fluvastatin ion in cell.
So which structure should be used when considering the structure ot this drug in chemoinformatics? Thank you.
For tamoxifen, one of its Synonyms is tamoxifen citrate shown in guidetopharmacology. In pubchem, they are different (CID 2733526 and 2733525) with the latter includes a citrate. At least in the Connectivity Map, tamoxifen citrate [54965-24-1] (as a catalog name) was used instead of tamoxifen (as a cmap_name) [ref1]. I think they are just different, resulting in different effect on cells. In this situation, should I use the structure of tamoxifen to discovery sth. in the Connectivity Map? It's a little odd. I'm wondering why they use tamoxifen citrate instead of tamoxifen, but name it as tamoxifen. Is it common for drug testing in chemstry?