I have a table of metabolite concentrations for ~100 metabolites in ~300 plant cultivars. Eventually I plan on running a GWAS to link these phenotypes to sequence data from these cultivars. I would also like to combine the metabolites into different clusters in case that increases power. I have run a PCA and simple hierarchical clustering in R, but I'm wondering whether there is another approach I should be using? If anyone has any recommendations they would be appreciated! I haven't been able to find any standard approach in a number of different GWAS papers I have looked at.