Hi My three year old son was diagnosed with FoxG1 deletion that is affecting him terribly (unable to sit walk talk eat, etc. I believe that with CRISPR if the FoxG1 Gene is edited / replaced, my son Kush should be cured. The question I have is how does the FoxG1 gene get created (synthesised ) in the first place.
The way I understand CRISPR will work is below, The Crisper CAS 9 will have the target corrected DNA / RNA for the FoxG1 gene attached to it a s a transport, once in the cell it will go and look for the Broken FoxG1 material , cut it out and replace that with the corrected FoxG1 RNA code.
Several questions here, 1. How long / big is the FoxG1 Gene RNA. How many base pairs long. 2. Is it possible to edit cut / paste the full FoxG1 to get rid of the defective code and replace with the correct code. 3. Another question is that the FoxG1 code that will be sent as a payload with the CRISPR CAS9 system, where do you get that from in the first place. Is this a synthesized material made using nanotechnology is this organic matter from donor cells from somewhere.
Excuse my ignorance if. I am am parent that wants their child fixed and i can raise money for this. does anyone want a grant to start working on this . I am all ears.
Please feel free to contact at anytime of day or night. TOGETHER WE WILL FIND A CURE