Where can I download hg18.fa that includes all chromosomes?
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7.9 years ago

In UCSC genome browser, the hg18 provided is not in one fasta file. They provide file to download for each chromosomes. May I know where can I download a hg18 complete fasta file that include all chromosomes? Thanks.

genome hg18 chromosome fasta • 5.2k views
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7.9 years ago

http://hgdownload.cse.ucsc.edu/downloads.html

Here, scroll down until you reach hg18 and then full dataset.

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After I clicked 'full dataset', the only way for me to get hg18.fa is by downloading hg18.2bit and use twoBitToFa to convert to hg18.fa right? is there any link allow me to straight away download the hg18.fa without doing the conversion from twoBitToFa? thanks for your advice

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Download the fasta files for each chromosome and use cat to concatenate them. Alternatively, find out the last Ensembl release to use hg18 and download that fasta file.

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This should give you full hg18 in one file from UCSC.

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The readme suggests that that's one file per-chromosome. I get the feeling that the multifasta file didn't become standard at UCSC until sometime after 2006.

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