Question: Database Of Patented Drugs
17
gravatar for Will
8.7 years ago by
Will4.5k
United States
Will4.5k wrote:

I'm doing a project looking for the genes which are affected by "drugs". I've processed the STITCH database which has gene-compound interactions. However, most of the compounds are not drugs ... while I don't have a hard definition of a "drug" my current working definition is a patented compound.

Does anyone know of a database which annotates this information: ie. database of patented compounds?

Also, if anyone has a better distinction between "drug" and compound I would be glad to hear it.

Thanks,

-Will

database drug • 2.9k views
ADD COMMENTlink modified 4.8 years ago by Biostar ♦♦ 20 • written 8.7 years ago by Will4.5k

What do you mean by patented drug? the drug that was patented or any biologically active compound that have patent?

ADD REPLYlink written 7.9 years ago by Vladimir Chupakhin520
14
gravatar for Simon Cockell
8.7 years ago by
Simon Cockell7.3k
Newcastle
Simon Cockell7.3k wrote:

Drugbank is a database of compounds that have a pharmaceutical effect. This would probably be a good starting point (it has info on around 4000 compounds)

ChEBI contains 'chemicals of biological interest'. It's a larger database but does have information about patents (in the XRefs, e.g. see oxytocin).

ADD COMMENTlink written 8.7 years ago by Simon Cockell7.3k

Therapeutic Target Database (TTD) is another option.

ADD REPLYlink written 7.6 years ago by Malachi Griffith17k
7
gravatar for Larry_Parnell
8.7 years ago by
Larry_Parnell16k
Boston, MA USA
Larry_Parnell16k wrote:

Importantly, you may want to keep in mind side effects. See SIDER: http://sideeffects.embl.de/ Although this database does not link drug to gene/protein, it could be where you go next for important information.

ADD COMMENTlink modified 8.7 years ago • written 8.7 years ago by Larry_Parnell16k
6
gravatar for Joerg Kurt Wegner
8.7 years ago by
Belgium
Joerg Kurt Wegner230 wrote:

Another source could be the FDA orange book.

Update 2011-05-29:

  • Check also DBPedia for drugs - here an example SPARQL query, which will return all drugs within DBPedia.
  • ChEMBL has its own drugstore section and allows downloading this information via the web interface. This should also provide a pretty good start.
ADD COMMENTlink modified 8.1 years ago • written 8.7 years ago by Joerg Kurt Wegner230

never came across that resource, thanks for the idea.

ADD REPLYlink written 8.7 years ago by Will4.5k
4
gravatar for Mary
8.7 years ago by
Mary11k
Boston MA area
Mary11k wrote:

Kegg Drug might have something useful as well: http://www.kegg.jp/kegg/drug/

ADD COMMENTlink written 8.7 years ago by Mary11k
2
gravatar for Mavj
8.4 years ago by
Mavj20
Mavj20 wrote:

Approved oncology drug set http://dtp.nci.nih.gov/branches/dscb/oncology_drugset_explanation.html

ADD COMMENTlink written 8.4 years ago by Mavj20

Add Pubchem http://pubchem.ncbi.nlm.nih.gov/ too?

ADD REPLYlink written 8.4 years ago by Mavj20

Plus Enhanced NCI database browser http://129.43.27.140/ncidb2/

ADD REPLYlink written 8.4 years ago by Mavj20
0
gravatar for Pawel Szczesny
8.4 years ago by
Pawel Szczesny3.2k
Poland
Pawel Szczesny3.2k wrote:

Minor comment - depending on the question you want to answer, it could be worth paying attention to differences between drugs and co-drugs (the latter increase susceptibility of target organism to another drug and are not used on their own). From my experience certain databases treat co-drugs as regular drugs, which might lead to interesting mistakes.

ADD COMMENTlink written 8.4 years ago by Pawel Szczesny3.2k
0
gravatar for Charu
8.0 years ago by
Charu0
Charu0 wrote:

where can i get database which shows patent on the same drug granted/rejected in one jurisdiction say US but rejected in anr say EU. pl mail me at charupatent@gmail.com

ADD COMMENTlink written 8.0 years ago by Charu0
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