Database Of Patented Drugs
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13.7 years ago
Will 4.5k

I'm doing a project looking for the genes which are affected by "drugs". I've processed the STITCH database which has gene-compound interactions. However, most of the compounds are not drugs ... while I don't have a hard definition of a "drug" my current working definition is a patented compound.

Does anyone know of a database which annotates this information: ie. database of patented compounds?

Also, if anyone has a better distinction between "drug" and compound I would be glad to hear it.

Thanks,

-Will

database drug • 4.8k views
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What do you mean by patented drug? the drug that was patented or any biologically active compound that have patent?

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14
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13.7 years ago

Drugbank is a database of compounds that have a pharmaceutical effect. This would probably be a good starting point (it has info on around 4000 compounds)

ChEBI contains 'chemicals of biological interest'. It's a larger database but does have information about patents (in the XRefs, e.g. see oxytocin).

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Therapeutic Target Database (TTD) is another option.

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13.7 years ago

Importantly, you may want to keep in mind side effects. See SIDER: http://sideeffects.embl.de/ Although this database does not link drug to gene/protein, it could be where you go next for important information.

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6
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13.7 years ago

Another source could be the FDA orange book.

Update 2011-05-29:

  • Check also DBPedia for drugs - here an example SPARQL query, which will return all drugs within DBPedia.
  • ChEMBL has its own drugstore section and allows downloading this information via the web interface. This should also provide a pretty good start.
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never came across that resource, thanks for the idea.

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13.7 years ago
Mary 11k

Kegg Drug might have something useful as well: http://www.kegg.jp/kegg/drug/

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13.4 years ago
Mavj ▴ 20

Approved oncology drug set http://dtp.nci.nih.gov/branches/dscb/oncology_drugset_explanation.html

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Plus Enhanced NCI database browser http://129.43.27.140/ncidb2/

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13.4 years ago

Minor comment - depending on the question you want to answer, it could be worth paying attention to differences between drugs and co-drugs (the latter increase susceptibility of target organism to another drug and are not used on their own). From my experience certain databases treat co-drugs as regular drugs, which might lead to interesting mistakes.

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13.0 years ago
Charu • 0

where can i get database which shows patent on the same drug granted/rejected in one jurisdiction say US but rejected in anr say EU. pl mail me at charupatent@gmail.com

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