Question: miRNAs interaction networks analysis
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gravatar for Sam
16 months ago by
Sam100
Sam100 wrote:

Hello all , what is the best approach for miRNA and predicted target gene (without expression data) interaction networks analysis?

mirnas networks • 820 views
ADD COMMENTlink modified 16 months ago by Leite340 • written 16 months ago by Sam100
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gravatar for svlachavas
16 months ago by
svlachavas560
Greece
svlachavas560 wrote:

Hello Sam,

i suppose you mean for a group of target genes, search for known miRNA regulators or infer novel predictions. DIANA is a nice place to start from my personal experience:

http://diana.imis.athena-innovation.gr/DianaTools/index.php?r=site/page&view=software http://diana.imis.athena-innovation.gr/DianaTools/index.php?r=taverna/index

Best,

Efstathios

ADD COMMENTlink written 16 months ago by svlachavas560

DIANA-microT web server is under maintenance, could introduce any other?

ADD REPLYlink written 16 months ago by Sam100

For a quick run, try miRDB http://www.mirdb.org/, but the choise is somewhat arbitary and up to you. Take a look also to the following review, it looks interesting:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187787/

ADD REPLYlink written 16 months ago by svlachavas560
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