This may be basic question. But I would like to know or hear some comments and advice about DE analytic tools. FYI, I have very limited knowledge in this field. I keep studying, though.
I would like to know which DE analytic tool is the best to identify DE genes in RNA-seq data. Especially, I would like to know advantage, weak point, and difference between DE analysis based on negative binomial model and based on Bayesian empirical approach.
I'm not sure whether I can entirely understand your detail expertise. But I can at least figure out starting point.
Thanks in advance. HJ