I'm new to bioinformatics and I'm trying to assemble many raw sequence reads from the SRA. (Sequencing done with Illumina HiSeq 2500). Most of the files contain between 115 M and 440 M bases, but some of the files have counts around 1.1 G bases. I know how to convert the data into formats such as .fastq and the like. I've looked around and found many assemblers, like SPAdes and Velvet. Can someone recommend an assembler can work quickly and effectively on a desktop computer (with 16 gb RAM)?
Thanks,
Grant
What should be the configuration of a desktop for basic bioinformatics works like molecular dynamics. Please let me know what amount of RAM and graphic cards should be installed?
Hi surovisaikia, welcome to Biostars. We generally discourage posting questions in existing questions. Please use the search function to go through existing similar questions and if this still does not yield the desired answers, open a new question, providing the necessary details on what exactly you are working on and (in this case) what your budget would be.