I have a question analysing RNA-seq data(I'm using DESeq2)
I'm willing to use 8 samples with high sequencing depth, and 6 samples with low sequencing depth.(About 4times lower).
Can I use these data to analysis in DESeq2?? Does DESeq2 normalizes these samples' count for using??
If I can't, could somebody point the direction to the method I can use all these samples??
Any help will be very very saving me... Thanks...