Question: What is CINWntUp and CINnormL?
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gravatar for louis-gil
10 weeks ago by
louis-gil0
louis-gil0 wrote:

What is CINWntUp and CINnormL?

I read a paper that uses this two things as classes but Im not sure what they represent. I imply that CIN is referring to Chromosomal instability but I don't know what WntUp & normL refer to. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214593/)

gene • 138 views
ADD COMMENTlink modified 10 weeks ago by Kevin Blighe35k • written 10 weeks ago by louis-gil0
1

Hello louis-gil!

It appears that your post has been cross-posted to another site: https://biology.stackexchange.com/questions/78814/question-what-is-cinwntup-and-cinnorml

This is typically not recommended as it runs the risk of annoying people in both communities.

ADD REPLYlink written 10 weeks ago by WouterDeCoster36k

I read a paper

Don't you think it would be useful to link us to that paper?

ADD REPLYlink written 10 weeks ago by WouterDeCoster36k

Thanks, I forgot to add the link.

ADD REPLYlink written 10 weeks ago by louis-gil0
1
gravatar for Kevin Blighe
10 weeks ago by
Kevin Blighe35k
Republic of Ireland
Kevin Blighe35k wrote:

Yes, CIN is chromosomal instability.

CINWntUp, in this context, relates to CIN in colon cancer samples in which the Wnt pathway is up-regulated. CINnormL relates to CIN in colon cancer samples that have a 'normal-like' expression profile.

Further details:

Kevin

ADD COMMENTlink written 10 weeks ago by Kevin Blighe35k
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