I have a matrix of TPM values from 27 different tissue types that I obtained from a database (thus, I don't have the read counts). The data comes from an RNA-seq experiment.
I want to make differential expression analysis, where the purpose is to find a set of genes that is specific for one of those tissue types.
Is this possible? I've used DESeq2 before but that starts from read counts, not TPM values. Since I am working with pig, there are not many available databases from which I can extract these markers genes.
Thank you in advance,