Question: Gene function prediction
0
gravatar for Pappu
18 months ago by
Pappu1.9k
Pappu1.9k wrote:

I am wondering if there is any good way to predict the function of a gene given the fact that hardly any literature exists on it.

rna-seq chip-seq • 437 views
ADD COMMENTlink written 18 months ago by Pappu1.9k

Have you tried standard annotation tools to see if they give you a clue of what the gene may be? Or are you drawing a blank from that type of analysis?

ADD REPLYlink written 18 months ago by genomax90k

Nothing came out from uniprot go annotation.

ADD REPLYlink written 18 months ago by Pappu1.9k

If you have the mRNA sequence of the gene, then use blastx to see to which other proteins in other species it aligns. If you get a 100% homology hit, for example, then you could easily infer function.

ADD REPLYlink modified 18 months ago • written 18 months ago by Kevin Blighe66k
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