I am playing around with genomestudio to do genotyping of 32 SNP arrays from human samples just to learn the technique
One of my SNPs in genome studio is such:
# Calls: 32
AA Freq: .125
AB Freq .250
BB Freq: .625
Minor Freq (MAF): .250
I looked at a few SNPs and can’t seem to find a pattern for how MAF is calculated from these genotype frequencies. Or is it not calculated from the genotype frequencies of my study? Or rather is it looked up in a table from hapmap, 1000 genomes etc?
I am familiar with the formula MAF=(2Ref. allele)/(2(Ref.allele + alternate. allele)), but have not been able to figure out how to determine MAFstarting with genotype frequencies or any other numbers that I have from the output of genomestudio.
I am very new to these types of studies, any point in the right direction would be greatly appreciated.