alignment tool for big data

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4.5 years ago

gbahramali ▴ 20

Length of my sequence is 7000000bp and I want to align with other sequences which tools are good for this

sequence • 834 views

ADD COMMENT • link updated 10 months ago by Ram 43k • written 4.5 years ago by gbahramali ▴ 20

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The 'answer' to this is you don't align sequences of that size, certainly not for multiple sequence alignment and phylogenetics.

You need to use an indirect approach such as aligning orthologues, or computing a mash tree.

ADD REPLY • link 4.5 years ago by Joe 21k

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I want to drow phylogenetics after multiple sequence alignment

ADD REPLY • link 4.5 years ago by gbahramali ▴ 20

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Please use ADD COMMENT/ADD REPLY when responding to existing posts to keep threads logically organized. SUBMIT ANSWER is for new answers to original question.

ADD REPLY • link 4.5 years ago by GenoMax 141k

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same question: how many genomes from BLAST hit should be considered for phylogeny tree analysis?

(Open the link, the title does not describe the question very well)

ADD REPLY • link 4.5 years ago by gb ★ 2.2k

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