Question: capture-based plasma cnv calling
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gravatar for lffu_0032
7 months ago by
lffu_003260
lffu_003260 wrote:

Hi, Is there any tools can be used to call CNV in capture-based plasma sequencing data? Thanks a lot.

ADD COMMENTlink modified 7 months ago by Kevin Blighe66k • written 7 months ago by lffu_003260
0
gravatar for Kevin Blighe
7 months ago by
Kevin Blighe66k
Kevin Blighe66k wrote:

You could try DNAcopy (R) or Control-FREEC, or just use a customised method that utilises circular binary segmentation (CBS) and adjusts for sequencing depth across samples / libraries and also GC content.

Kevin

ADD COMMENTlink modified 7 months ago • written 7 months ago by Kevin Blighe66k
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