The gene names ending with *like suffix ?

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3.6 years ago

sunnykevin97 ▴ 980

HI

I work with non-model organisms, after DGE analysis, I find a lot of genes found significant the gene names ends with *like. I'm unable to find detailed information about these genes. For annotation I used Danio rerio Rlibrary.

Ex: zinc fingers and homeoboxes protein 1-like not much information available on web, does this gene has similar function like zinc fingers and homeoboxes protein 1

suggestions encouraged.

RNA-Seq • 761 views

ADD COMMENT • link 3.6 years ago by sunnykevin97 ▴ 980

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The interpretation may be based on simple sequence similarity searches/alignment. That is likely not enough evidence to conclude that the function is going to be similar to the gene being compared to.

ADD REPLY • link 3.6 years ago by GenoMax 141k

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I agree, the better way is to look into conserved domains between two proteins/genes. Is it right ?

ADD REPLY • link 3.6 years ago by sunnykevin97 ▴ 980

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https://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi try this.

ADD REPLY • link 3.6 years ago by pinn ▴ 210

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