Hi all, I have two objectives for my analysis:
- To find out denovo and rare variants from autism trios analysis
Trios: (Father, Mother, Proband)
- To detect frequently occuring mutation across autism patient.
I have used GATK best practice to identify the germline variants across 15 trios (
Total 45 samples [15X3]) and I have generated
gVCF file for all the 45 samples.
Can some one guide me how to call
de novo variants from this trios cohort?