Hi,I am second year student doing PhD in Bioinformatics. I had been working on many projects ,mostly involved in tool development and web server/database related applications. Some works involved both analysis and development. Now i wonder what kind of structure does the thesis should be based on? I see many examples on web are based on single project topic often. Till now all the works i have done has been in the microbiome domain,so should the thesis in general be single topic or can be combinations of all the projects that i have done ? As they are the research works that i have done during the study period.