Hi all, I was just wondering if this would be a legitimate strategy before putting in a lot of effort. Or if it's been done before.
I have a many, many single end runs of Illumina. Most are 1x70bp. I was thinking that if I split each of the raw reads into a 2x35 set, then maybe a scaffolder like SOPRA could help me bridge gaps. Is this crazy? If it's not crazy, are there any recommendations?