Question: Can I Write A Research Paper Based On The Results Of Comparing Computational Predictions Of Two Proteins
gravatar for Lavanya
7.4 years ago by
Lavanya50 wrote:

I have modelled a membrane protein using Insight-2 and glide's-prime. In insight - 2 I have modelled the whole protein, whereas in glide-prime I modeeled only a particular region. can I communicate this work as a comparison of prediction by these 2 methods? or can anyone suggest how I can frame these 2 works and send for publication in journal

publication • 1.4k views
ADD COMMENTlink modified 7.4 years ago by justinhaselbach250 • written 7.4 years ago by Lavanya50

See also: Do you know any outer membrane protein which do not have a beta-barrel structure?

I am not sure what the requirements are for getting papers on protein models accepted, but sometimes the best way to find out might be to actually submit a paper. Personally, I would be a bit skeptical about a model without any experimental validation. So, if you could get or find some experimental data or known structure to compare your model with that might improve things, though I heard getting crystal structure of membrane proteins is harder than other proteins. Also, why don't you make a full model from both programs. The way you are describing it now sound as if the models are not really comparable.

ADD REPLYlink modified 7.4 years ago • written 7.4 years ago by Michael Dondrup47k
gravatar for justinhaselbach
7.4 years ago by
United States
justinhaselbach250 wrote:

You MUST Publish if the following are true-

  1. Similar data-sets have been published in 'some journal'. !
  2. The study is enough IN-DEPTH.
  3. There is NOVEL information available after your study on the protein's- structure, function or similar aspects.
  4. And yes, DATA without analyses and biological significance is a "house of bricks and NOT home" !

Good to be in touch with a biologist, to be able to find out more on this as well.


ADD COMMENTlink written 7.4 years ago by justinhaselbach250
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1678 users visited in the last hour