I had read same papers, but I met a simple question:
What is the definition of gene cluster (in the level of genes distribute on chromosomes)?
(papers: Large clusters of co-expressed genes in the Drosophila genome, Clustering of housekeeping genes provides a unified model of gene order in the human genome)
Could anyone give me a example about how to calculate a gene cluster?
It seems they define a cluster as physically adjacent genes, but the distance between two genes may vary a great deal across the genome. So what is the permissible distance between two genes in a cluster?
I think you are talking about "gene family". I remember in <[?]> there is tip about "clustering of gene family(homology) and adjacent genes(distribution on chromosomes) are different". But I feel confused now...