Dating Common Ancestor

Question

[Adrian Pelin]

Hello,

I have 10 strains sequenced with NGS, and I have called polymorphisms and was able to reconstruct a phylogeny of these strains.

The bad news is that I do no have an outgroup, since the strains are very similar to each other and there is no available reference sequenced. The good news is that different isolates are from different time points (years), spanning 2007 to 2011. Some isolates are from the same year.

What is the best tool to try and date the last common ancestor?

Adrian

[Prakki Rama]

Would beast software be useful for you?

[farahdeeba19]

BEAST has terminated with an error. Please selectMay 31, 2015 12:00:58 AM dr.app.beast.BeastMain <init>
SEVERE: Parsing error - poorly formed BEAST file, f1.xml:
Error parsing '<ancestralTreeLikelihood>' element with id, 'treeLikelihood':
Ancestral state functionality is only support when using the BEAGLE library.
Available from http://http://beagle-lib.googlecode.com/
java.lang.RuntimeException: Terminate
    at dr.app.beast.BeastMain.<init>(Unknown Source)
    at dr.app.beast.BeastMain.main(Unknown Source)
 QUIT from the menu.

This is the message every time I run beast

Could anybody please help me out

farah

[Brian Bushnell]

The title of your post is kind of funny... I misread it at first :)

[WouterDeCoster]

I wonder how the date went, perhaps they are married with children by now.