Difference between RNA Seq and Microarray

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17 months ago

anasjamshed ▴ 120

What is the difference between Microarray and RNA-seq Analysis methods? Why do we take one over the other?

microarray RNA-seq • 538 views

ADD COMMENT • link updated 17 months ago by Ram 43k • written 17 months ago by anasjamshed ▴ 120

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RNA-seq vs. Microarray

Why do we take one over the other?

Cost can certainly be one factor. Arrays are a proven technology and can still be cheaper option if one is happy with the design of the array. Illumina has some information/references at this link that compare microarray and RNAseq.

ADD REPLY • link 17 months ago by GenoMax 141k

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There are quite a few answers to this question. They measure expression in different ways (fluorescence vs counting), thus require different analysis methods. A simple google search on one vs the other brings up plenty of articles to pursue. Or you can use pubmed to find a comparison such as Comparison of RNA-Seq and Microarray...(2019), follow the references in that paper, or follow the "Similar Articles" section on pubmed.

ADD REPLY • link 17 months ago by seidel 11k

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Is this an assignment question? What have you searched for so far and what have you understood from whatever you've learned on this topic?

ADD REPLY • link 17 months ago by Ram 43k

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