Recent Votes
Recent Locations •
All
South Korea, 1 minute ago
Germany, 2 minutes ago
Hannover Medical School, 4 minutes ago
Germany, 4 minutes ago
Hong Kong, 5 minutes ago
USA, 5 minutes ago
Iran, 5 minutes ago
Recent Awards •
All
Popular Question to
Wietje
▴
220
Popular Question to
Michael Dondrup
49k
Popular Question to
diego1530
▴
40
Popular Question to
Mehmet
▴
670
Popular Question to
kspata
▴
70
Recent Replies
Answer: How do you generate TMM normalized counts using EdgeR?
by
ATpoint
50k
The default normalization in edgeR can be broken down to two steps:
----------
1) normalization by library size. That is simply the cor…
Comment: directionality of RRBS
by
Papyrus
▴
880
Yes, it is normal! Remember that RRBS does not profile the whole genome in an unbiased manner. Instead, it generates enzimatically-ennriche…
Answer: filtering dataframe using multiple columns in R
by
PeterKW
▴
30
library(data.table)
df= fread("data.txt", sep = " ", header = T)`
CGDid Mass Source.File …
Comment: Difference between KO and ko numbers?
by
deep771992chanda
▴
30
Thanks andres. But here it says that
> "ko reference pathway highlighting KOs''
So it seems confusing to me. Can you please explain t…
Comment: output TMM normalized counts with edgeR
by
Gordon Smyth
★
2.6k
`cpm()` uses TMM normalization factors automatically.
The edgeR documentation advises users not to use `pseudo.counts` but instead to use …
Comment: Using Linear Regression on Genotype and Expression data
by
PeterKW
▴
30
Can you show the model that you are fitting?
Comment: Looking for data
by
Mollie
•
0
I have a hapmap1.gen file and I think that the .bim version can be used as the phenotype because of the column arrangement?
heres the GenE…
Comment: What are DNA-related genes?
by
Zhilong Jia
★
1.8k
A suggestion: a better definition and explanation of `DNA-related genes` will clarify this question and probably solve this question by you…
Answer: How do you generate TMM normalized counts using EdgeR?
by
Gordon Smyth
★
2.6k
Sorry this has been confusing. This has also been a regular source of frustration for the edgeR authors as well because we have been saying…
Comment: GATK Input files reference and features have incompatible contigs: No overlappin
by
Jordi
•
0
I downloaded them from the official [gnomAD download page][1]
[1]: https://gnomad.broadinstitute.org/downloads#v2-variants
Answer: Difference between KO and ko numbers?
by
andres.firrincieli
★
1.3k
Hello,
> I could not understand what is the difference between KO and ko IDs?
> Are they similar or different?
KO and ko IDs are the…
Comment: directionality of RRBS
by
basuanubhav
▴
30
Thanks for that.
So I checked the same sample in both directional and non-directional alignment and found that the mapping efficiency stay…
Comment: How can I extract protein sequence from gff file?
by
cpad0112
16k
Please do not post the images of the data instead of posting data.
Answer: How to tell if our ligand-protein docking is good from AutoDock Vina's result
by
Mensur Dlakic
★
11k
I always consider two criteria when evaluating similar results: binding affinity and biological relevance. Pose 1 is the best according to …
Comment: Produce PCA bi-plot for 1000 Genomes Phase III - Version 2
by
sayyarsehrish
•
0
sorry, my understanding is very low in bioinformatics and I want to plot the PCA graph using Rstudio. i have used plink for the generation …
Traffic: 1229 users visited in the last hour
Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by the
version 2.3.6
version 2.3.6