How to get ortholog sequences.
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7.1 years ago
syrup16g_TO ▴ 40

Hi, everyone.

 

I want to get the sequence pair of ortholog.

e.g. For AGO2, I want to get the human AGO2 amino-acid sequence and the rat AGO2 amino-acid sequence.

 

Thank you.

Sequence Ortholog • 2.7k views
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7.1 years ago
PoGibas 4.9k

After searching here on biostars.org I found OMA Browser (http://omabrowser.org/cgi-bin/gateway.pl).

This is quick and easy way to find orthologs for a single gene.
 

http://omabrowser.org/cgi-bin/gateway.pl?p1=AGO2&f=SearchDb

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7.1 years ago
Coryza ▴ 400

How about... http://www.uniprot.org/uniprot/?query=AGO2&sort=score

?

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7.1 years ago
Biojl ★ 1.7k

You can get the information at ensembl biomart. Input your list of genes and then select attributes/homologs/orthologs for the species you need.

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cdsouthan ★ 1.9k

Adapting from Pgbas  www.uniprot.org/uniprot/?query=AGO2_RAT&sort=score gets you straight there

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