Question: Program To Find Synonymous Codon From Sequence
0
gravatar for Saran
7.6 years ago by
Saran0
Saran0 wrote:

hello can anyone tell me how to find synonymous codon from DNA sequence..

perl code • 2.0k views
ADD COMMENTlink written 7.6 years ago by Saran0
6

Please read your question back to yourself and ask whether you would bother to answer it in its current form.

ADD REPLYlink written 7.6 years ago by Neilfws48k
1
gravatar for Chris
7.6 years ago by
Chris1.6k
Munich
Chris1.6k wrote:

Google could be useful sometimes...

http://www.bio-technologies.info/about/genetic/genetic-coding

ADD COMMENTlink written 7.6 years ago by Chris1.6k
1
gravatar for Stevelor
7.6 years ago by
Stevelor310
Stevelor310 wrote:

Also notice the different translation tables....

ADD COMMENTlink written 7.6 years ago by Stevelor310
0
gravatar for mcc
7.4 years ago by
mcc80
PVD, USA
mcc80 wrote:

Hi Saran, I know of two companies that are or were (not sure which) working on this type of problem. One was Coda Genomics (now defunct) but you can look up Rick Lathrop. And the second is Perkin Elmer. I believe they both have patents as well. I believe that RL's patent uses thermodynamic calculations to determine the 'best' codon sequence while PE's uses melting point. Very interesting ideas.

Q. May I ask what you have found out, if anything? M

ADD COMMENTlink written 7.4 years ago by mcc80

do you mean you suggest buying a commercial product only for translating a DNA to protein ?

ADD REPLYlink written 7.4 years ago by Pierre Lindenbaum119k

@Pierre: I am not suggesting you (or anyone) should buy anything. I am saying that there is enough interest in finding alternative codon sequences that would produce 'your protein of interest' such that two companies have filed (both I believe have been awarded) patents. This technology could be very useful in producing very large dna segments which might self-assemble via melting pt or thermodynamic properties. As you may know, there are practical limits to length of man made dna. Wouldn't it be useful to increase that by a factor of 10, 100, 1000, etc.

ADD REPLYlink written 7.4 years ago by mcc80
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