Hi, I have illumina 2x150 bp from a metagenomics experiment. This is not 16S data but WGS data.
I was wondering if either DEseq2 or edgeR can be used for data normalization in this context ? I know these two are normally used for RNA data but it looks they might also perform well with DNA data (based on this article "Statistical evaluation of methods for identification of differentially abundant genes in comparative metagenomics"
Thanks for your comments, David